KMID : 0371420231040020101
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Annals of Surgical Treatment and Research 2023 Volume.104 No. 2 p.101 ~ p.108
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Clinical outcomes of gastric cancer surgery after liver transplantation
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Kim Sun-Joo
Lee Hyuk-Joon Fadhel Alzahrani Kim Jee-Sun Kim Sa-Hong Kim Sa-Ra Cho Yo-Seok Park Ji-Hyeon Lee Jeong-Moo Kong Seong-Ho Park Do-Joong Suh Kyung-Suk Yang Han-Kwang
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Abstract
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Purpose: De novo malignancy is common after liver transplantation (LT); however, there are limited reports on the clinical outcomes of gastric cancer surgery after LT. Our study aimed to investigate the feasibility and safety of gastric cancer surgery after LT.
Methods: Seventeen patients underwent gastric cancer surgery after LT at a single institution between January 2013 and June 2021. We retrospectively collected data on surgical complications, survival, and recurrence status of these cases.
Results: Fifteen patients (88.2%) underwent curative gastrectomy, with 10 open distal (66.7%) and 5 laparoscopic distal (33.3%) gastrectomies. Surgical and severe complication rates were 3 of 15 (20.0%) and 1 of 15 (6.7%), respectively. There were no significant differences between laparoscopic (33.3%) and open surgery (66.7%) in terms of operation time and complication rate. No surgery-related mortalities occurred. Immunosuppressants could be maintained without difficulty, and no suspicious acute rejection was identified during the perioperative period. There was 1 recurrence after curative surgery (recurrence rate, 6.7%), and the 5-year cancer-specific survival rate after curative surgery was 93.3%.
Conclusion: Laparoscopic gastrectomy can be safely done even after LT in terms of postoperative complications and graft safety.
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KEYWORD
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Gastrectomy, Liver transplantation, Stomach neoplasms
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